Saturday, March 5, 2016

Skin appendages

The skin contains the following appendages.
• Each hair is composed of a medulla, cortex and outer cuticle.
• The hair follicle consists of an inner root sheath, derived from the epidermis, and
an outer root sheath, derived from the dermis.
• Several sebaceous glands drain into each follicle. Discharge from these glands is
aided by the contraction of erector pili muscles.
• Velus hairs are fine and downy.
• Terminal hairs are coarse.
• Hairs are in either the telogen or the anogen phase.
• 75% of hairs are in the anogen (growth) phase at any one time.
• The remaining 25% of hairs are in the telogen (resting) phase.
• These sweat glands secrete an odourless hypotonic fluid.
• They are present in all sites of the body.
• Eccrine glands occur more frequently in the eyelids, palms, feet and axilla.
• These are located in the axilla and groin.
• They emit a thicker secretion than eccrine glands.
• They are responsible for body odour.
• Hidradenitis suppurativa is an infection of the apocrine glands.
• These are holocrine glands that usually drain into the pilosebaceous unit.
1• They drain directly onto the skin in the labia, penis and tarsus (meibomian
glands).
• They occur more frequently on the forehead, nose and cheek.
• Sebaceous glands are not the sole cause of so-called sebaceous cysts. These cysts
are in fact of epidermal origin and contain all of the substances secreted by the skin
(predominantly keratin).
• Some authorities maintain that they should therefore be called epidermoid
cysts.
• Eccrine or merocrine glands secrete opened vesicles via exocytosis.
• Apocrine glands secrete unbroken vesicles which later discharge.
• Holocrine glands secrete whole cells which then disintegrate.
• Acanthosisahyperplasia of the epithelium.
• Papillomatosisaan increase in the depth of the corrugations at the junction
between epidermis and dermis.
• Hyperkeratosisaan increase in the thickness of the keratin layer.

• Parakeratosisathe presence of nucleated cells at the skin surface.