Saturday, March 5, 2016

Skin appendages

The skin contains the following appendages.
Each hair is composed of a medulla, cortex and outer cuticle.
The hair follicle consists of an inner root sheath, derived from the epidermis, and
an outer root sheath, derived from the dermis.
Several sebaceous glands drain into each follicle. Discharge from these glands is
aided by the contraction of erector pili muscles.
Velus hairs are fine and downy.
Terminal hairs are coarse.
Hairs are in either the telogen or the anogen phase.
75% of hairs are in the anogen (growth) phase at any one time.
The remaining 25% of hairs are in the telogen (resting) phase.
These sweat glands secrete an odourless hypotonic fluid.
They are present in all sites of the body.
Eccrine glands occur more frequently in the eyelids, palms, feet and axilla.
These are located in the axilla and groin.
They emit a thicker secretion than eccrine glands.
They are responsible for body odour.
Hidradenitis suppurativa is an infection of the apocrine glands.
These are holocrine glands that usually drain into the pilosebaceous unit.
1• They drain directly onto the skin in the labia, penis and tarsus (meibomian
glands).
• They occur more frequently on the forehead, nose and cheek.
• Sebaceous glands are not the sole cause of so-called sebaceous cysts. These cysts
are in fact of epidermal origin and contain all of the substances secreted by the skin
(predominantly keratin).
• Some authorities maintain that they should therefore be called epidermoid
cysts.
• Eccrine or merocrine glands secrete opened vesicles via exocytosis.
• Apocrine glands secrete unbroken vesicles which later discharge.
• Holocrine glands secrete whole cells which then disintegrate.
Acanthosisahyperplasia of the epithelium.
Papillomatosisaan increase in the depth of the corrugations at the junction
between epidermis and dermis.
Hyperkeratosisaan increase in the thickness of the keratin layer.

Parakeratosisathe presence of nucleated cells at the skin surface.